Predicting chemotherapy-induced menopause using baseline and post-chemotherapy anti-Mullerian hormone levels: Results of a pilot study.

ABSTRACT:

Background

Chemotherapy can cause premature menopause which may result in adverse effects such as fertility loss, osteoporosis, cardiovascular disease and menopausal symptoms. It is thus very important that women are provided with accurate information regarding their risk of premature menopause as a consequence of proposed chemotherapy. Unfortunately, at present there are no reliable tools which can be applied in clinical practice to estimate the risk of premature menopause in women undergoing chemotherapy, beyond age of the patient and form of chemotherapy utilized.

Aim

This was a pilot study to determine whether AMH levels pre and during chemotherapy are able to predict for chemotherapy induced menopause, and to assess quality of life and menopausal symptoms.

Methods an

SUBMITTER: Martin HL 

PROVIDER: S-EPMC8222560 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature