Association of consciousness impairment and mortality in people with COVID-19.

ABSTRACT:

Background

To investigate the association between impairment of consciousness and risk of death in people with COVID-19.

Methods

In this multicentre retrospective study, we enrolled people with confirmed COVID-19 from 44 hospitals in Wuhan and Sichuan, China, between 18 January and 30 March 2020. We extracted demographics, clinical, laboratory data and consciousness level (as measured by the Glasgow Coma Scale (GCS) score) from medical records. We used Cox proportional hazards regression, structural equation modelling and survival time analysis to compare people with different progressions of impaired consciousness.

Results

We enrolled 1,143 people (average age 51.3 ± standard deviation 17.1-year-old; 50.3% males), of whom 76 died. Increased mortality risk was identif

SUBMITTER: Xiong W 

PROVIDER: S-EPMC8222878 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature