Transcriptome-Wide Analysis of RNA m⁶A Methylation and Gene Expression Changes Among Two Arabidopsis Ecotypes and Their Reciprocal Hybrids.

ABSTRACT: The remodeling of transcriptome, epigenome, proteome, and metabolome in hybrids plays an important role in heterosis. N(6)-methyladenosine (m⁶A) methylation is the most abundant type of post-transcriptional modification for mRNAs, but the pattern of inheritance from parents to hybrids and potential impact on heterosis are largely unknown. We constructed transcriptome-wide mRNA m⁶A methylation maps of Arabidopsis thaliana Col-0 and Landsberg erecta (Ler) and their reciprocal F₁ hybrids. Generally, the transcriptome-wide pattern of m⁶A methylation tends to be conserved between accessions. Approximately 74% of m⁶A methylation peaks are consistent between the parents and hybrids, indicating that a majority of the m⁶

SUBMITTER: Xu Z 

PROVIDER: S-EPMC8222996 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature