COVID-19 patients with obesity at risk for worse outcomes despite younger age and fewer inflammatory derangements.

ABSTRACT:

Background

Coronavirus disease 2019 (COVID-19) is a viral pulmonary infection that can progress to cytokine storm syndrome because of widespread dysregulated inflammatory response. Many patients at risk for severe COVID-19 manifestation have been identified as those with preexisting conditions of pulmonary origin, as well as conditions that impair appropriate immune response, such as obesity.

Objectives

The aim of this study is to describe the manifestation, clinical course, and inflammatory biomarker milieu of COVID-19 in patients with obesity.

Setting

University Hospital Philadelphia, Pennsylvania.

Methods

In this retrospective cohort study, 600 patients who were positive for COVID-19 were stratified by World Health Organization (WHO) obesity class and their

SUBMITTER: Le Guen CL 

PROVIDER: S-EPMC8223125 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature