Prevalence of Coronary Artery Disease and Coronary Microvascular Dysfunction in Patients With Heart Failure With Preserved Ejection Fraction.

ABSTRACT:

Importance

Coronary artery disease (CAD) and coronary microvascular dysfunction (CMD) may contribute to the pathophysiologic characteristics of heart failure with preserved ejection fraction (HFpEF). However, the prevalence of CAD and CMD have not been systematically studied.

Objective

To examine the prevalence of CAD and CMD in hospitalized patients with HFpEF.

Design, setting, and participants

A total of 106 consecutive patients hospitalized with HFpEF were evaluated in this prospective, multicenter, cohort study conducted between January 2, 2017, and August 1, 2018; data analysis was performed from March 4 to September 6, 2019. Participants underwent coronary angiography with guidewire-based assessment of coronary flow reserve, index of microvascular resistance, an

SUBMITTER: Rush CJ 

PROVIDER: S-EPMC8223134 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature