Retrobulbar Hemangioblastomas in von Hippel-Lindau Disease: Clinical Course and Management.

ABSTRACT:

Background

Retrobulbar hemangioblastomas involving the optic apparatus in patients with von Hippel-Lindau disease (VHL) are rare, with only 25 reported cases in the literature.

Objective

To analyze the natural history of retrobulbar hemangioblastomas in a large cohort of VHL patients in order to define presentation, progression, and management.

Methods

Clinical history and imaging of 250 patients with VHL in an ongoing natural history trial and 1774 patients in a neurosurgical protocol were reviewed. The clinical course, magnetic resonance images, treatment, and outcomes were reviewed for all included patients.

Results

A total of 18 patients with retrobulbar hemangioblastoma on surveillance magnetic resonance imaging met the inclusion criteria for this study. O

SUBMITTER: Alvarez R 

PROVIDER: S-EPMC8223245 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature