Modeling and Synthesis of Breast Cancer Optical Property Signatures With Generative Models.

ABSTRACT: Is it possible to find deterministic relationships between optical measurements and pathophysiology in an unsupervised manner and based on data alone? Optical property quantification is a rapidly growing biomedical imaging technique for characterizing biological tissues that shows promise in a range of clinical applications, such as intraoperative breast-conserving surgery margin assessment. However, translating tissue optical properties to clinical pathology information is still a cumbersome problem due to, amongst other things, inter- and intrapatient variability, calibration, and ultimately the nonlinear behavior of light in turbid media. These challenges limit the ability of standard statistical methods to generate a simple model of pathology, requiring more advanced algorithms. We pre

SUBMITTER: Pardo A 

PROVIDER: S-EPMC8224479 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature