Ethnic Identity and Genome Wide Runs of Homozygosity.

ABSTRACT: It is long known that inbreeding increases the detrimental effects of recessive sequence variants in "Runs of Homozygosity" (ROHs). However, although the phenotypic association of ROH has been investigated for a variety of traits, the statistical power of the results often remains limited as a sufficiently high number of cases are available for only a restricted number of traits. In the present study, we aim to analyze the association of runs of homozygosity with the trait "in-group ethnic favoritism". This analysis assumes that if ethnic identity is important for an individual, that individual may tend to marry more frequently within their own group and therefore ROH are expected to increase. We hypothesize that an attitude preferring one's own ethnic group may be associated with a strong

SUBMITTER: Fieder M 

PROVIDER: S-EPMC8225526 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature