Increased levels of inflammatory markers in the subscapularis tendon and joint capsule in patients with subacromial impingement.

ABSTRACT:

Purpose

To analyze biopsy samples from the subscapularis tendon and from the joint capsule from male patients with subacromial impingement syndrome and compare them with samples from male patients with post-traumatic recurrent shoulder instability, to detect increased inflammatory activity that might be present inside the humeroscapular joint.

Methods

Twenty male patients scheduled for surgery for either subacromial decompression or Bankart reconstruction were included. Four biopsies from each patient were obtained during surgery from the capsule and the subscapularis tendon. Each specimen was analyzed for TNF-α, IL-6, CD-3 and CD-72. Multiplex fluorescence immunohistochemistry was performed on histological samples from the capsule and tendon to demonstrate the level of infl

SUBMITTER: Farfaras S 

PROVIDER: S-EPMC8225532 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature