Influence of osteoporosis on the compressive properties of femoral cancellous bone and its dependence on various density parameters.

ABSTRACT: Data collection of mechanical parameters from compressive tests play a fundamental role in FE modelling of bone tissues or the developing and designing of bone implants, especially referring to osteoporosis or other forms of bone loss. A total of 43 cylindrical samples (Ø8 × 16 mm) were taken from 43 freshly frozen proximal femora using a tenon cutter. All femora underwent BMD measurement and additionally apparent- and relative- and bulk density (ρ_app, ρ_r, ρ_b) were determined using samples bordering the compressive specimen on the proximal and distal regions. All samples were classified as "normal", "osteopenia" and "osteoporosis" based on the DEXA measurements. Distal apparent density was most suitable for predicting bone strength and BMD. One novel aspect

SUBMITTER: Metzner F 

PROVIDER: S-EPMC8225914 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature