Single-Cell Transcriptomics Reveals the Cellular Heterogeneity of Cardiovascular Diseases.

ABSTRACT: "A world in a wild flower, and a bodhi in a leaf," small cells contain huge secrets. The vasculature is composed of many multifunctional cell subpopulations, each of which is involved in the occurrence and development of cardiovascular diseases. Single-cell transcriptomics captures the full picture of genes expressed within individual cells, identifies rare or de novo cell subpopulations, analyzes single-cell trajectory and stem cell or progenitor cell lineage conversion, and compares healthy tissue and disease-related tissue at single-cell resolution. Single-cell transcriptomics has had a profound effect on the field of cardiovascular research over the past decade, as evidenced by the construction of cardiovascular cell landscape, as well as the clarification of cardiovascul

SUBMITTER: Fu M 

PROVIDER: S-EPMC8225933 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature