Supernormal lung function and risk of COPD: A contemporary population-based cohort study.

ABSTRACT:

Background

Investigation of the natural history of chronic obstructive pulmonary disease (COPD) has led to the recognition that individuals with higher than normal lung function may have lower risk of developing COPD. We tested the hypothesis that individuals with supernormal lung function have lower risk of COPD.

Methods

We followed 108,246 adults from the Copenhagen General Population Study recruited between 2003 and 2015 for clinical COPD outcomes until 2018. A subset of 16,892 attended another examination approximately 10 years later, allowing to investigate lung function decline and COPD development (forced expiratory volume in 1 se (FEV₁)/forced vital capacity (FVC)<0·70 and FEV₁<80% predicted with chronic respiratory symptom). Supernormal lung fu

SUBMITTER: Colak Y 

PROVIDER: S-EPMC8225980 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature