Estimating the Breast Cancer Burden in Germany and Implications for Risk-based Screening.

ABSTRACT: In Germany, it is currently recommended that women start mammographic breast cancer screening at age 50. However, recently updated guidelines state that for women younger than 50 and older than 70 years of age, screening decisions should be based on individual risk. International clinical guidelines recommend starting screening when a woman's 5-year risk of breast cancer exceeds 1.7%. We thus compared the performance of the current age-based screening practice with an alternative risk-adapted approach using data from a German population representative survey. We found that 10,498,000 German women ages 50-69 years are eligible for mammographic screening based on age alone. Applying the 5-year risk threshold of 1.7% to individual breast cancer risk estimated from a model that considers a wom

SUBMITTER: Quante AS 

PROVIDER: S-EPMC8226107 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature