TGF-β expression on different suturing technique for abdominal skin wound closure in rats.

ABSTRACT:

Background

The method of closing the abdominal wall, as well as, the choice of material for stitching are important aspects of efficient incision closure. Generally, transforming growth factor-beta (TGF-β) is involved in the wound healing process. Suturing procedures also play a part in the wound dehiscence occurrence. This study aimed to compare TGF-β expressions in rats after using the large stitch vs. small stitch technique for abdominal skin wound closure.

Methods

A total of twenty Wistar rats (Rattus norvegicus) were used in this experiment. Small tissue bites of 5 mm were obtained by the small stitch group and the large stitch group received large bites of 10 mm. Abdominal skin incisions were closed by running sutures. On days 4 and 7, the animals were euthanize

SUBMITTER: Sofii I 

PROVIDER: S-EPMC8226395 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature