Colonic Volume Changes in Paediatric Constipation Compared to Normal Values Measured Using MRI.

ABSTRACT:

Background

Functional constipation in children is common. Management of this condition can be challenging and is often based on symptom reports. Increased, objective knowledge of colonic volume changes in constipation compared to health could provide additional information. However, very little data on paediatric colonic volume is available except from methods that are invasive or require unphysiological colonic preparations.

Objectives

(1) To measure volumes of the undisturbed colon in children with functional constipation (FC) using magnetic resonance imaging (MRI) and provide initial normal range values for healthy controls, and (2) to investigate possible correlation of colonic volume with whole gut transit time (WGTT).

Methods

Total and regional (ascending, trans

SUBMITTER: Sharif H 

PROVIDER: S-EPMC8226615 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature