Wa-1 Equine-Like G3P[8] Rotavirus from a Child with Diarrhea in Colombia.

ABSTRACT: Rotavirus A (RVA) has been considered the main cause of diarrheal disease in children under five years in emergency services in both developed and developing countries. RVA belongs to the Reoviridae family, which comprises 11 segments of double-stranded RNA (dsRNA) as a genomic constellation that encodes for six structural and five to six nonstructural proteins. RVA has been classified in a binary system with Gx[Px] based on the spike protein (VP4) and the major outer capsid glycoprotein (VP7), respectively. The emerging equine-like G3P[8] DS-1-like strains reported worldwide in humans have arisen an important concern. Here, we carry out the complete genome characterization of a previously reported G3P[8] strain in order to recognize the genetic diversity of RVA circulating among in

SUBMITTER: Martinez-Gutierrez M 

PROVIDER: S-EPMC8226935 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature