Aquaporins Are Differentially Regulated in Canine Cryptorchid Efferent Ductules and Epididymis.

ABSTRACT: The efferent ductules and the epididymis are parts of the male reproductive system where spermatozoa mature. Specialized epithelial cells in these ducts contribute to the transport of fluids produced by spermatozoa's metabolic activity. Aquaporins (AQPs) have been demonstrated to be expressed in the spermatozoan membrane and testis epithelial cells, where they contribute to regulating spermatozoan volume and transit through environments of differing osmolality. Due to the lack of detailed literature regarding AQP expression in the canine male genital tract, the aim of this study was to investigate both the distribution and expression of AQP7, AQP8, and AQP9 in the efferent ductules and epididymal regions (caput, corpus, and cauda) from normal and cryptorchid dogs by using immunohistochemis

SUBMITTER: Squillacioti C 

PROVIDER: S-EPMC8227126 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature