A Comprehensive Phylogenetic and Bioinformatics Survey of Lectins in the Fungal Kingdom.

ABSTRACT: Fungal lectins are a large family of carbohydrate-binding proteins with no enzymatic activity. They play fundamental biological roles in the interactions of fungi with their environment and are found in many different species across the fungal kingdom. In particular, their contribution to defense against feeders has been emphasized, and when secreted, lectins may be involved in the recognition of bacteria, fungal competitors and specific host plants. Carbohydrate specificities and quaternary structures vary widely, but evidence for an evolutionary relationship within the different classes of fungal lectins is supported by a high degree of amino acid sequence identity. The UniLectin3D database contains 194 fungal lectin 3D structures, of which 129 are characterized with a carbohydrate ligan

SUBMITTER: Lebreton A 

PROVIDER: S-EPMC8227253 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature