Graphene Quantum Dots from Carbonized Coffee Bean Wastes for Biomedical Applications.

ABSTRACT: Recent studies concerning graphene quantum dots (GQDs) focus extensively on their application in biomedicine, exploiting their modifiable optical properties and ability to complex with various molecules via π-π or covalent interactions. Among these nascent findings, the potential therapeutic efficacy of GQDs was reported against Parkinson's disease, which has to date remained incurable. Herein, we present an environmentally friendly approach for synthesizing GQDs through a waste-to-treasure method, specifically from coffee waste to nanodrug. Consistent with the previous findings with carbon fiber-derived GQDs, the inhibitory effects of coffee bean-derived GQDs demonstrated similar effectiveness against abnormal α-synuclein fibrillation and the protection of neurons from relevant subcellula

SUBMITTER: Kim DJ 

PROVIDER: S-EPMC8228242 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature