Cancer Vaccines for Genitourinary Tumors: Recent Progresses and Future Possibilities.

ABSTRACT:

Background

In the last years, many new treatment options have widened the therapeutic scenario of genitourinary malignancies. Immunotherapy has shown efficacy, especially in the urothelial and renal cell carcinomas, with no particular relevance in prostate cancer. However, despite the use of immune checkpoint inhibitors, there is still high morbidity and mortality among these neoplasms. Cancer vaccines represent another way to activate the immune system. We sought to summarize the most recent advances in vaccine therapy for genitourinary malignancies with this review.

Methods

We searched PubMed, Embase and Cochrane Database for clinical trials conducted in the last ten years, focusing on cancer vaccines in the prostate, urothelial and renal cancer.

Results

Various the

SUBMITTER: Maiorano BA 

PROVIDER: S-EPMC8228524 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature