The impact of caries status on supragingival plaque and salivary microbiome in children with mixed dentition: a cross-sectional survey.

ABSTRACT:

Background

Supragingival plaque and saliva are commonly used for microbiome analysis. Many epidemiological studies have identified deciduous teeth caries as a risk factor for caries development in first permanent molar (FPM); nevertheless, to the best of our knowledge, there are no reports on the effects of deciduous teeth caries on the microbiome of healthy FPM. Additionally, it remains unclear whether saliva can be used instead of supragingival plaque for caries microbial studies. Therefore, we aimed to elucidate this issue, and to characterize and compare the oral microbiome of healthy FPMs in children with different caries statuses and that from children with and without caries in a similar microhabitat, by PacBio sequencing. Currently, few studies have investigated the oral mi

SUBMITTER: Yang X 

PROVIDER: S-EPMC8229229 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature