The Peculiar Trialogue between Pediatric Obesity, Systemic Inflammatory Status, and Immunity.

ABSTRACT: Pediatric obesity is not only an energetic imbalance, but also a chronic complex multisystem disorder that might impair both the life length and quality. Its pandemic status should increase worldwide awareness regarding the long-term life-threatening associated complications. Obesity related complications, such as cardiovascular, metabolic, or hepatic ones, affect both short and long-term wellbeing, and they do not spare pediatric subjects, defined as life-threatening consequences of the systemic inflammatory status triggered by the adipose tissue. The energetic imbalance of obesity clearly results in adipocytes hypertrophy and hyperplasia expressing different degrees of chronic inflammation. Adipose tissue might be considered an immune organ due to its rich content in a complex array of i

SUBMITTER: Melit LE 

PROVIDER: S-EPMC8229553 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature