Impact of rural versus urban setting on kidney markers: a cross-sectional study in South-Kivu, DRCongo.

ABSTRACT:

Background

Most studies of chronic kidney disease (CKD) in Sub-Saharan Africa (SSA) have been conducted in urban settings. They relied on GFR estimated from serum creatinine alone and on the inexpensive, convenient urinary dipstick to assess proteinuria. The dipstick for proteinuria has not been directly compared with the gold standard albumin-to-creatinine ratio (ACR) in a large-sized study in SSA. We hereby assessed the influence of rural versus urban location on the level, interpretation, and diagnostic performance of proteinuria dipstick versus ACR.

Methods

In a cross-sectional population-based study of CKD in both urban (n = 587) and rural (n = 730) settings in South-Kivu, Democratic Republic of Congo (DRC), we assessed the prevalence, performance (sensitivity, specific

SUBMITTER: Masimango MI 

PROVIDER: S-EPMC8229682 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature