Multichannel near-infrared spectroscopy brain imaging system for small animals in mobile conditions.

ABSTRACT: Significance: We propose a customized animal-specific head cap and an near-infrared spectroscopy (NIRS) system to obtain NIRS signals in mobile small animals. NIRS studies in mobile small animals provide a feasible solution for comprehensive brain function studies. Aim: We aim to develop and validate a multichannel NIRS system capable of performing functional brain imaging along with a closed-box stimulation kit for small animals in mobile conditions. Approach: The customized NIRS system uses light-weight long optical fibers, along with a customized light-weight head cap to securely attach the optical fibers to the mouse. A customized stimulation box was designed to perform various stimuli in a controlled environment. The system performance was tested in a visual stimu

SUBMITTER: Paik SH 

PROVIDER: S-EPMC8230091 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature