Association between the FTO SNP rs9939609 and Metabolic Syndrome in Chilean Children.

ABSTRACT: The increasing prevalence of obesity in children has raised the incidence of Metabolic Syndrome (MetS) in this age group. Given the short- and long-term health impact of MetS, it is essential to prevent its onset by detecting its main triggers. Besides, genetic factors play an essential role in influencing which individuals within a population are most likely to develop obesity in response to a particular environment. In this regard, a common variation in the FTO gene is reproducibly associated with BMI and obesity from childhood and the genetic load has been linked to several cardiovascular risk factors, highlighting the FTO single nucleotide polymorphism (SNP) rs9939609. Therefore, this study aimed to establish the relationship between the FTO SNP rs9939609 and MetS. A cross-sectional st

SUBMITTER: Molina-Luque R 

PROVIDER: S-EPMC8230726 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature