Methodological review to develop a list of bias items used to assess reviews incorporating network meta-analysis: protocol and rationale.

ABSTRACT:

Introduction

Systematic reviews with network meta-analysis (NMA; ie, multiple treatment comparisons, indirect comparisons) have gained popularity and grown in number due to their ability to provide comparative effectiveness of multiple treatments for the same condition. The methodological review aims to develop a list of items relating to biases in reviews with NMA. Such a list will inform a new tool to assess the risk of bias in NMAs, and potentially other reporting or quality checklists for NMAs which are being updated.

Methods and analysis

We will include articles that present items related to bias, reporting or methodological quality, articles assessing the methodological quality of reviews with NMA, or papers presenting methods for NMAs. We will search Ovid MEDLINE, the

SUBMITTER: Lunny C 

PROVIDER: S-EPMC8231030 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature