Ontology highlight
ABSTRACT:
SUBMITTER: Henrique C
PROVIDER: S-EPMC8231604 | biostudies-literature | 2021 Jun
REPOSITORIES: biostudies-literature
Henrique Camila C Falcão Maria Alice Pimentel MAP De Araújo Pimenta Luciana L Maleski Adolfo Luís Almeida ALA Lima Carla C Mitsunari Thais T Sampaio Sandra Coccuzzo SC Lopes-Ferreira Mônica M Piazza Roxane Maria Fontes RMF
Toxins 20210612 6
Heat-labile toxin I (LT-I), produced by strains of enterotoxigenic <i>Escherichia coli</i> (ETEC), causes profuse watery diarrhea in humans. Different in vitro and in vivo models have already elucidated the mechanism of action of this toxin; however, their use does not always allow for more specific studies on how the LT-I toxin acts in systemic tracts and intestinal cell lines. In the present work, zebrafish (<i>Danio rerio</i>) and human intestinal cells (Caco-2) were used as models to study t ...[more]