Sinking Our Teeth in Getting Dental Stem Cells to Clinics for Bone Regeneration.

ABSTRACT: Dental stem cells have been isolated from the medical waste of various dental tissues. They have been characterized by numerous markers, which are evaluated herein and differentiated into multiple cell types. They can also be used to generate cell lines and iPSCs for long-term in vitro research. Methods for utilizing these stem cells including cellular systems such as organoids or cell sheets, cell-free systems such as exosomes, and scaffold-based approaches with and without drug release concepts are reported in this review and presented with new pictures for clarification. These in vitro applications can be deployed in disease modeling and subsequent pharmaceutical research and also pave the way for tissue regeneration. The main focus herein is on the potential of dental stem cells for ha

SUBMITTER: Shoushrah SH 

PROVIDER: S-EPMC8232184 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature