A clinical diabetes risk prediction model for prediabetic women with prior gestational diabetes.

ABSTRACT:

Introduction

Without treatment, prediabetic women with a history of gestational diabetes mellitus (GDM) are at greater risk for developing type 2 diabetes compared with women without a history of GDM. Both intensive lifestyle intervention and metformin can reduce risk. To predict risk and treatment response, we developed a risk prediction model specifically for women with prior GDM.

Methods

The Diabetes Prevention Program was a randomized controlled trial to evaluate the effectiveness of intensive lifestyle intervention, metformin (850mg twice daily), and placebo in preventing diabetes. Data from the Diabetes Prevention Program (DPP) was used to conduct a secondary analysis to evaluate 11 baseline clinical variables of 317 women with prediabetes and a self-reported history o

SUBMITTER: Man B 

PROVIDER: S-EPMC8232404 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature