Infection-Associated Peripheral Nerve Hyperexcitability: An Under-Recognized Entity.

ABSTRACT:

Background

Peripheral nerve hyperexcitability (PNH) and neuromyotonia have been mainly attributed to antibodies against voltage-gated potassium channels (VGKC). Concurrent autoimmune disorders, malignancies, and heavy metal toxicity have also been implicated. There is scarce mention about infection as a triggering factor for PNH. There are no reports of methicillin-resistant Staphylococcus aureus (MRSA) infection being a possible precipitating factor for development of PNH.

Methods

Case series and literature review.

Results

Four subjects were diagnosed to have features of PNH based on clinical and electrophysiological assessment. All the subjects had concurrent evidence of cutaneous abscesses requiring surgical intervention and antibiotic therapy. The cultures

SUBMITTER: Sivadasan A 

PROVIDER: S-EPMC8232500 | biostudies-literature | 2021 Mar-Apr

REPOSITORIES: biostudies-literature