Spontaneous eye movements during eyes-open rest reduce resting-state-network modularity by increasing visual-sensorimotor connectivity.

ABSTRACT: During wakeful rest, individuals make small eye movements during fixation. We examined how these endogenously driven oculomotor patterns impact topography and topology of functional brain networks. We used a dataset consisting of eyes-open resting-state (RS) fMRI data with simultaneous eye tracking. The eye-tracking data indicated minor movements during rest, which correlated modestly with RS BOLD data. However, eye-tracking data correlated well with echo-planar imaging time series sampled from the area of the eye-orbit (EO-EPI), which is a signal previously used to identify eye movements during exogenous saccades and movie viewing. Further analyses showed that EO-EPI data were correlated with activity in an extensive motor and sensorimotor network, including components of the dorsal atten

SUBMITTER: Koba C 

PROVIDER: S-EPMC8233114 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature