Quantifying and Assessing the Dosimetric Impact of Changing Gas Volumes Throughout the Course of VMAT Radiation Therapy of Upper Gastrointestinal Tumors.

ABSTRACT:

Purpose

This retrospective patient study assessed the consistency of abdominal gas presence throughout radiation therapy for patients with upper gastrointestinal cancer and determined the impact of variations in gas volume on the calculated dose distribution of volumetric modulated arc therapy.

Methods and materials

Eight patients with pancreatic cancer were included for analysis. A plan library consisting of 3 reference plans per patient (Ref_0.0, Ref_0.5, and Ref_1.0) was created based on planning computed tomography (CT) with density overrides of 0.0, 0.5, and 1.0 applied to gas volumes, respectively. Corresponding cone beam CT (CBCT) data sets were obtained and density overrides were applied to enable fractional dose calculation. Variation i

SUBMITTER: Scott J 

PROVIDER: S-EPMC8233468 | biostudies-literature | 2021 May-Jun

REPOSITORIES: biostudies-literature