Ontology highlight
ABSTRACT:
SUBMITTER: Pylaeva E
PROVIDER: S-EPMC8234083 | biostudies-literature | 2021 Jun
REPOSITORIES: biostudies-literature
Pylaeva Ekaterina E Ozel Irem I Squire Anthony A Spyra Ilona I Wallner Charlotte C Korek Magdalena M Korschunow Georg G Domnich Maksim M Siakaeva Elena E Goetz Moritz M Bankfalvi Agnes A Lang Stephan S Kansy Benjamin B Jablonska Jadwiga J
Cancers 20210621 12
The role of neutrophils during cancer formation and elimination is diverse. Here, for the first time, we investigate neutrophil helper cells (N<sub>BH</sub>), their influence on B cell activity in the regional lymph nodes (RLN) of head-and-neck cancer patients and the effect of this neutrophil/B cell interaction on patient prognosis. Circulating and RLN neutrophils of patients with stage I-IV head-and-neck squamous cell carcinoma were investigated with flow cytometry and qPCR. In addition, neutr ...[more]