Reliability of the mean flow index (Mx) for assessing cerebral autoregulation in healthy volunteers.

ABSTRACT:

Background

Mean flow index (Mxa) for evaluating dynamic cerebral autoregulation is derived using varying approaches for calculation, which may explain that the reliability ranges from poor to excellent. The comparability, repeatability, stability, and internal consistency of approaches have not previously been assessed.

Methods

We included 60 recordings from resting healthy volunteers and calculated Mxa using four different approaches: three without overlapping calculations, using intervals for averaging wave-form data (blocks) of 3, 6, and 10 s, and correlation periods (epochs) of 60, 240, and 300 s (3-60-F, 6-240-F, and 10-300-F); and one using 10-second blocks, 300 s epochs, and overlaps of 60 s (10-300-60). The comparability between the approaches was assessed using Stud

SUBMITTER: Olsen MH 

PROVIDER: S-EPMC8234479 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature