Shockwave Lithotripsy Versus Ureteroscopic Treatment as Therapeutic Interventions for Stones of the Ureter (TISU): A Multicentre Randomised Controlled Non-inferiority Trial.

ABSTRACT:

Background

Renal stone disease is common and can cause emergency presentation with acute pain due to ureteric colic. International guidelines have stated the need for a multicentre randomised controlled trial (RCT) to determine whether a non-invasive outpatient (shockwave lithotripsy [SWL]) or surgical (ureteroscopy [URS]) intervention should be the first-line treatment for those needing active intervention. This has implications for shaping clinical pathways.

Objective

To report a pragmatic multicentre non-inferiority RCT comparing SWL with URS.

Design, setting, and participants

This trial tested for non-inferiority of up to two sessions of SWL compared with URS as initial treatment for ureteric stones requiring intervention.

Outcome measurements and statistical a

SUBMITTER: Dasgupta R 

PROVIDER: S-EPMC8234516 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature