A Prospective Study of Etiological Agents Among Febrile Patients in Sierra Leone.

ABSTRACT:

Introduction

Sierra Leone has one of the highest burdens of febrile illnesses in the world. As the incidence of malaria diminishes, a better understanding of the spectrum of etiological agents was important for accurate diagnosis and empirical treatment of febrile illness.

Methods

Blood, nasopharyngeal, and fecal specimens were collected from febrile patients for serological, molecular detection, and microbiologic culture to identify potential pathogens.

Results

For this prospective study, 142 febrile patients were enrolled. The prevalence of malaria was higher in children aged 5-15 years old (P = 0.185) and adults (P = 0.018). Acute respiratory infection (ARI) presented more commonly in the under 5 years old group (P = 0.009). For diarrhea, all children groups (P = 0

SUBMITTER: Wang H 

PROVIDER: S-EPMC8234757 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature