The Effect of Functional Fiber on Microbiota Composition in Different Intestinal Segments of Obese Mice.

ABSTRACT: The gastrointestinal tract is a heterogeneous ecosystem with distinct, stratified environments, which leads to different microbial composition in different intestinal segments. The regional heterogeneity of intestinal microbiota complicates the relationship between diet and microbiota. Few studies have focused on the effects of different diets on microbiota in different intestinal segments. This study aimed to investigate the effects of functional fiber on the microbial composition in multiple intestinal segments from a high-fat diet compared with a normal chow diet. We found that the response of microbiota from different intestinal segments to diet was related to the intestinal physiologic function and the physicochemical properties of dietary nutrients. A high-fat diet drove changes in t

SUBMITTER: Xu C 

PROVIDER: S-EPMC8234870 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature