Circulating Non-Coding RNAs as a Signature of Autism Spectrum Disorder Symptomatology.

ABSTRACT: Autism spectrum disorder (ASD) is a multifaced neurodevelopmental disorder that becomes apparent during early childhood development. The complexity of ASD makes clinically diagnosing the condition difficult. Consequently, by identifying the biomarkers associated with ASD severity and combining them with clinical diagnosis, one may better factionalize within the spectrum and devise more targeted therapeutic strategies. Currently, there are no reliable biomarkers that can be used for precise ASD diagnosis. Consequently, our pilot experimental cohort was subdivided into three groups: healthy controls, individuals those that express severe symptoms of ASD, and individuals that exhibit mild symptoms of ASD. Using next-generation sequencing, we were able to identify several circulating non-codin

SUBMITTER: Salloum-Asfar S 

PROVIDER: S-EPMC8235321 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature