Dataset Information

Non-Occupational Exposure to Pesticides: Experimental Approaches and Analytical Techniques (from 2019).

ABSTRACT: Pesticide residues are a threat to the health of the global population, not only to farmers, applicators, and other pesticide professionals. Humans are exposed through various routes such as food, skin, and inhalation. This study summarizes the different methods to assess and/or estimate human exposure to pesticide residues of the global population. A systematic search was carried out on Scopus and web of science databases of studies on human exposure to pesticide residues since 2019. The methods to estimate human health risk can be categorized as direct (determining the exposure through specific biomarkers in human matrices) or indirect (determining the levels in the environment and food and estimating the occurrence). The role that analytical techniques play was analyzed. In both cases, the application of generic solvent extraction and solid-phase extraction (SPE) clean-up, followed by liquid or gas chromatography coupled to mass spectrometry, is decisive. Advances within the analytical techniques have played an unquestionable role. All these studies have contributed to an important advance in the knowledge of analytical techniques for the detection of pesticide levels and the subsequent assessment of nonoccupational human exposure.

SUBMITTER: Vera-Herrera L

PROVIDER: S-EPMC8235395 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature

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Publications

Non-Occupational Exposure to Pesticides: Experimental Approaches and Analytical Techniques (from 2019).

Vera-Herrera Lucía L Sadutto Daniele D Picó Yolanda Y

Molecules (Basel, Switzerland) 20210616 12

<h4>Background</h4>Pesticide residues are a threat to the health of the global population, not only to farmers, applicators, and other pesticide professionals. Humans are exposed through various routes such as food, skin, and inhalation. This study summarizes the different methods to assess and/or estimate human exposure to pesticide residues of the global population.<h4>Methods</h4>A systematic search was carried out on Scopus and web of science databases of studies on human exposure to pestici ...[more]

PMID: 34208757

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Project description:A better understanding of environmental exposure to agricultural pesticides is crucial for public health, regulatory and management purposes. Residents in close vicinity to agricultural fields are likely to be more exposed to pesticides. In that context, an innovative geospatial approach for mapping estimates of agricultural pesticide exposure was developed in this study. Data on pesticide application rates, high-resolution annual datasets of the geographic distribution of crops, and the 100 × 100m grid population dataset were utilized to complete this analysis in Wallonia (Belgium) over the period 2015-2019. Pesticide exposure metrics were estimated using a buffer-based exposure model by conducting neighborhood analysis within a 1000m buffer radius. Subsequently, a population weighted method was used to 'up-scale' the exposure data to administrative levels. In a limited validation effort, model estimates were compared with pesticide measurements in air collected at 12 stations during the period 2015-2016. The results present the first modeling map of environmental exposure to agricultural pesticides for the whole of the Walloon region. The northern part of the Sambre-Meuse axis demonstrates more intensive agriculture and the highest pesticide weighted exposure indices. The majority of the population resides near agricultural areas, with only 4 % living in regions that lack crops within a 1000m radius, primarily in the central areas of large cities. A positive trend association between pesticide measures in air and the index was observed at the different stations, nevertheless further validation efforts are needed to accurately compare the same active ingredients. This work gives a valuable basis for research and environmental health actions in Belgium. Maps highlight areas where human biomonitoring and epidemiological studies should be implemented to investigate the impact of potential environmental exposure to pesticides. This information helps policy-makers to take measures to control and reduce the load of agricultural pesticides in the environment.

Dataset Information

Non-Occupational Exposure to Pesticides: Experimental Approaches and Analytical Techniques (from 2019).

Publications

Non-Occupational Exposure to Pesticides: Experimental Approaches and Analytical Techniques (from 2019).

Similar Datasets

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