Effects of temperature on proliferation of myoblasts from donor piglets with different thermoregulatory maturities.

ABSTRACT:

Background

Climate change and the associated risk for the occurrence of extreme temperature events or permanent changes in ambient temperature are important in the husbandry of farm animals. The aim of our study was to investigate the effects of permanent cultivation temperatures below (35 °C) and above (39 °C, 41 °C) the standard cultivation temperature (37 °C) on porcine muscle development. Therefore, we used our porcine primary muscle cell culture derived from satellite cells as an in vitro model. Neonatal piglets have limited thermoregulatory stability, and several days after birth are required to maintain their body temperature. To consider this developmental step, we used myoblasts originating from thermolabile (five days of age) and thermostable piglets (twenty days of age).

SUBMITTER: Metzger K 

PROVIDER: S-EPMC8236195 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature