LED control of gene expression in a nanobiosystem composed of metallic nanoparticles and a genetically modified E. coli strain.

ABSTRACT:

Background

Within the last decade, genetic engineering and synthetic biology have revolutionized society´s ability to mass-produce complex biological products within genetically-modified microorganisms containing elegantly designed genetic circuitry. However, many challenges still exist in developing bioproduction processes involving genetically modified microorganisms with complex or multiple gene circuits. These challenges include the development of external gene expression regulation methods with the following characteristics: spatial-temporal control and scalability, while inducing minimal permanent or irreversible system-wide conditions. Different stimuli have been used to control gene expression and mitigate these challenges, and they can be characterized by the effect they p

SUBMITTER: Aratboni HA 

PROVIDER: S-EPMC8236197 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature