Subclinical Anxiety and Posttraumatic Stress Influence Cortical Thinning During Adolescence.

ABSTRACT:

Objective

Adolescence is a sensitive period for the development and emergence of anxiety and mood disorders. Research suggests that symptoms ranging from subclinical to clinical levels are associated with pathological developmental changes in the neocortex. However, much of this research has been cross-sectional, limiting the field's ability to identify the neurodevelopmental impacts of these symptoms. The present study examined how early reported symptoms predict baseline cortical thickness and surface area, and trajectories of change in these measures during adolescence.

Method

A total of 205 typically developing individuals 9 to 15 years of age (103 male and 102 female participants) completed 3T structural magnetic resonance imaging annually for 3 years. From these, we ex

SUBMITTER: Taylor BK 

PROVIDER: S-EPMC8236497 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature