Multi-structure Cortical States Deduced From Intracellular Representations of Fixed Tactile Input Patterns.

ABSTRACT: The brain has a never-ending internal activity, whose spatiotemporal evolution interacts with external inputs to constrain their impact on brain activity and thereby how we perceive them. We used reproducible touch-related spatiotemporal sensory inputs and recorded intracellularly from rat (Sprague-Dawley, male) neocortical neurons to characterize this interaction. The synaptic responses, or the summed input of the networks connected to the neuron, varied greatly to repeated presentations of the same tactile input pattern delivered to the tip of digit 2. Surprisingly, however, these responses tended to sort into a set of specific time-evolving response types, unique for each neuron. Further, using a set of eight such tactile input patterns, we found each neuron to exhibit a set of specific

SUBMITTER: Norrlid J 

PROVIDER: S-EPMC8236821 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature