Ten-year survival analysis of patients with primary Sjogren's syndrome in China: a national prospective cohort study.

ABSTRACT:

Aims

To investigate the long-term survival of patients with primary Sjögren's syndrome (pSS) in China.

Methods

Patients with pSS who fulfilled the 2002 American-European Consensus Group classification criteria were prospectively enrolled from 2004 to 2011. Their baseline clinical, laboratory, and therapeutic data were collected. The primary endpoint was all-cause death by January 2018. The standard mortality ratio (SMR) was calculated by comparing with age-matched and sex-matched mortality data of the general population. Kaplan-Meier curves were obtained by time-to-event analysis. Univariate and multivariate Cox hazards regression analyses were performed to identify risk factors for mortality.

Results

A total of 1054 patients were enrolled and 834 patients were follow

SUBMITTER: Qian J 

PROVIDER: S-EPMC8237224 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature