Non-alcoholic fatty liver disease is associated with increased risk of chronic kidney disease.

ABSTRACT:

Background and aims

Whether non-alcoholic fatty liver disease (NAFLD) is associated with an increased risk of incident chronic kidney disease (CKD) independent of established cardio-renal risk factors remains controversial. We aimed to provide a quantitative estimate of the association and strength between NAFLD and risk of CKD after adjustment for multiple cardio-renal risk factors.

Methods

We searched electronic databases (PubMed, Embase, and Google Scholar) for studies published from database inception until 30 November 2020. Analysis included cohort studies that reported multivariable-adjusted risk ratios [including odds ratios, relative risks (RRs), or hazard ratios] and 95% confidence intervals (CIs) for CKD of NAFLD compared with individuals without NAFLD.

Results<

SUBMITTER: Cai X 

PROVIDER: S-EPMC8237225 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature