Nanoparticles prepared from pterostilbene reduce blood glucose and improve diabetes complications.

ABSTRACT:

Background

Diabetes complications are the leading cause of mortality in diabetic patients. The common complications are decline in antioxidant capacity and the onset of micro-inflammation syndrome. At present, glucose-responsive nanoparticles are widely used, as they can release insulin-loaded ultrafine particles intelligently and effectively reduce blood sugar. However, the toxicology of this method has not been fully elucidated. The plant extracts of pterostilbene (PTE) have a wide range of biological applications, such as antioxidation and inflammatory response improvement. Therefore, we have proposed new ideas for the cross application of plant extracts and biomaterials, especially as part of a hypoglycaemic nano-drug delivery system.

Results

Based on the PTE, we success

SUBMITTER: Zhao X 

PROVIDER: S-EPMC8237509 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature