COVID-19 Pathology on Various Organs and Regenerative Medicine and Stem Cell-Based Interventions.

ABSTRACT: Severe acute respiratory syndrome-coronavirus 2, a novel betacoronavirus, has caused the global outbreak of a contagious infection named coronavirus disease-2019. Severely ill subjects have shown higher levels of pro-inflammatory cytokines. Cytokine storm is the term that can be used for a systemic inflammation leading to the production of inflammatory cytokines and activation of immune cells. In coronavirus disease-2019 infection, a cytokine storm contributes to the mortality rate of the disease and can lead to multiple-organ dysfunction syndrome through auto-destructive responses of systemic inflammation. Direct effects of the severe acute respiratory syndrome associated with infection as well as hyperinflammatory reactions are in association with disease complications. Besides acute res

SUBMITTER: Arjmand B 

PROVIDER: S-EPMC8238122 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature