Treatments of unruptured brain arteriovenous malformations: A systematic review and meta-analysis.

ABSTRACT:

Background

The best therapeutic option for unruptured brain arteriovenous malformations (bAVMs) patients is disputed.

Objective

To assess the occurrence of obliteration and complications of patients with unruptured bAVMs after various treatments.

Methods

A systematic literature search was performed in PubMed, EMBASE, Web of Science, and so on to identify studies fulfilling predefined inclusion criteria. Baseline, treatment, and outcomes data were extracted for statistical analysis.

Results

We identified 28 eligible studies totaling 5852 patients. The obliteration rates were 98% in microsurgery group (95% confidence interval (CI): 96%-99%, I2 = 74.5%), 97% in surgery group (95%CI: 95%-99%, I2 = 18.3%), 87% in endovascular treatment group (95%CI: 80%-93%, I2 = 0.

SUBMITTER: Liu R 

PROVIDER: S-EPMC8238300 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature