Allergy-related diseases and early gut fungal and bacterial microbiota abundances in children.

ABSTRACT:

Background

The early gut microbiota has been proposed as an important link between environmental exposures and development of allergy-related diseases. Beyond the widely investigated associations between the gut bacterial microbiota, we investigated the involvement of early gut mycobiota and gut permeability in the pathogenesis of asthma, allergic rhinoconjunctivitis (AR) and eczema.

Methods

In the Probiotics in the Prevention of Allergy among Children in Trondheim trial with maternal probiotic supplementation, we collected faecal samples at four timepoints between 0 and 2 years from a cohort of 278 children. Clinical information on allergy-related diseases was collected in a paediatric examination at 2 years and questionnaires at 6 weeks and 1, 2 and 6 years. By quantitativ

SUBMITTER: Schei K 

PROVIDER: S-EPMC8238386 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature