Competing interplay between systemic and periodontal inflammation: obesity overrides the impact of oral periphery.

ABSTRACT:

Objectives

We aimed at investigating whether the interaction between the local inflammation, periodontitis, and obesity is independently associated with systemic inflammation.

Methods

From the population-based Study of Health in Pomerania, 3366 participants, without (2366) and with (1000) obesity, were studied for the association of periodontitis, measured as probing depth (PD) and plaque together with body mass index (BMI) on C-reactive protein (CRP). Quantile regression was used to evaluate the association between periodontal, anthropometric, and inflammatory variables (outcomes).

Results

The overall prevalence of obesity in this adult population was 31.4% in men and 28.1% in women. Both PD and plaque were positively associated with CRP, revealing an increasing impa

SUBMITTER: Meisel P 

PROVIDER: S-EPMC8238770 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature